Home - Products - Angiogenesis - PKC - Protein kinase inhibitor H-7 dihydrochloride

Protein kinase inhibitor H-7 dihydrochloride

CAS No. 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride( —— )

Catalog No. M33862 CAS No. 108930-17-2

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 43 Get Quote
10MG 72 Get Quote
25MG 150 Get Quote
50MG 242 Get Quote
100MG 380 Get Quote
500MG 861 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Protein kinase inhibitor H-7 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.
  • Description
    Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    108930-17-2
  • Formula Weight
    364.29
  • Molecular Formula
    C14H19Cl2N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 16.67 mg/mL (45.76 mM; Ultrasonic (<80°C)
  • SMILES
    Cl.Cl.CC1CNCCN1S(=O)(=O)c1cccc2cnccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fischer SM, et al. Mediation of phorbol ester-induced oxidant generation in murine epidermal cells by protein kinase C. Toxicol In Vitro. 1989;3(3):195-9. ?
molnova catalog
related products
  • Hispidin

    Hispidin is a polyphenol originally including antioxidant anti-inflammatory and cytoprotective properties.

  • ZIP

    Novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.

  • Protein kinase inhib...

    Protein kinase inhibitor H-7 is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.